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🐾 Calm, collected, and confidently yours — because your big buddy deserves peace of mind!
Zylkene Calming Supplements deliver a clinically proven 450mg dose of natural alpha casozepine per capsule, expertly formulated for large dogs (30-60kg). Trusted as the UK’s top veterinary calming aid, it supports pets through short-term stressors like loud noises and social gatherings. Easy to administer and allergen-free, this 20-capsule pack offers convenient, vet-approved relief to help your dog stay relaxed and happy wherever life takes you.











| ASIN | B00K06M9QC |
| Age Range Description | Adult |
| Age range (description) | Adult |
| Allergen Information | Allergen-Free |
| Benefits | Brain Health Support |
| Best Sellers Rank | 582 in Pet Supplies ( See Top 100 in Pet Supplies ) 26 in Relaxants & Anxiety Relief for Dogs |
| Brand | Zylkene |
| Brand Name | Zylkene |
| Colour | White & Blue |
| Country Of Origin | France |
| Customer Reviews | 4.1 out of 5 stars 4,332 Reviews |
| Dosage Form | Capsule |
| Flavour | Unflavoured |
| Included Components | nil |
| Item Dimensions | 6 x 6 x 17 centimetres |
| Item Form | Capsule |
| Item Nype Name | Relaxants & Anxiety Relief for Large Dogs |
| Item Weight | 450 Milligrams |
| Item form | Capsule |
| Manufacturer | Vetoquinol |
| Manufacturer Contact Information | Vetoquinol UK Ltd, Steadings Barn, Pury Hill Business Park, Nr Alderton, Towcester, Northamptonshire NN12 7LS |
| Manufacturer Part Number | 3605874361775 |
| Model Name | Zylkene |
| Model Number | 3605874361775 |
| Number of Items | 1 |
| Primary Supplement Type | Casein |
| Primary supplement type | Casein |
| Product Warranty | 2 year manufacturer |
| Product benefits | Brain Health Support |
| Specific Uses For Product | Behaviour |
| Supplement Formulation | Individual Supplement |
| Unit Count | 20.0 count |
A**T
OMG I cant praise this enough
If I could give this ten stars I would ! We have an old dog suffering from dementia. He is physically in excellent health but was suffering from severe stress and a condition named Sundown which was very horrible for him. He would become seriously agitated at night and pace in circles wimping. During the day he hardly responded and his eyes looked vacant and dull. We were at the point of having him pts. I remembered using the equine version on a horse and it worked to settle him in competition. So I gave it a go not really very hopefull. Within two days he was more settled. He continued to improve and has been on it now for a month and the Sundown no longer bothers him. His eyes are bright and he is now enjoying life. No longer dragging on walks and his appetite is healthy again. He is still an old dog but a normal old dog. No longer stressed and confused. No pacing and staring. I cant beleive the difference we have our dog back. He is fed the dose for a large dog although he is a labrador and med.
N**N
Life saver
For my older dog, who had symptoms very much like dementia, these have made such a difference. He did have episodes during the day, but night time was always the worst. He would wake up panting, pacing around, anxious, and nothing I did seemed to settle him. It could last the entire night. Since trying these, the change has been amazing. We’re all finally sleeping through the night again, with no constant pacing or barking. They are pricey, but for the peace and a full night’s sleep, they’ve been worth every penny.
B**Y
Short term solution
I brought this for my girl dog when her brother unfortunately passed and she was so upset. Seems to be having some effect but did not help during a storm last night. Maybe needs to build up in the system before full effect is reached
B**S
Easy to give as if it's a dog treat
It took the edge off a fear of fireworks without causing any drowsiness. A couple of my dogs will take the blue capsule whole, like a treat yet the older one spat it out so it got emptied into their food bowl instead.
R**N
How to achieve peace and quiet night or day living with an unrelaxed cat
This definitely calms my cat, and previous cats. I administer it in a needle less syringe, first dissolving it in a tiny pot in about one and a half ml of water which has been measured in the syringe, then stirred with my finger until dissolved. You need to syringe it in several small squirts as slowly as possible. Give the cat some treats or bit of tasty food afterwards: why? Because cats will look forward to this and put aside their dislike of the procedure.BUT you really need to go slowly with the syringe, maybe you should Google using a syringe for oral cat medications.
B**E
Works
Works really well for my chihuahua before long journeys (she does not like the car)
L**G
Contact amazon?
The calming supplements work and calm our rough collier who has anxiety issues. However trying to contact amazon regarding the subscription costs is terrible! So I'm left with having to write my complaint on a review. I have tried different ways of making contact with customer services but end up going in circles. My complaint is we were charged £37.20 per packet of tablets(we ordered 3) when the cost without subscription is £34.97. We have a subscription and the cost should have been £29.72. Why have we been charged so much more!
M**R
Great but open the capsule 💊 not to be given whole
Doing ok so far watch out though !!!!!! I didn’t read the packet and you DO NOT GIVE AS A TABLET !! You break open the capsule 💊 and empty on food !! Didn’t do that 1st time so hope he will be ok 👌🏻 so stupid of me !! As they were capsules 💊 so I didn’t think ?
D**O
Dovreste domandare al mio cane
Lo tranquillizza
C**.
Calmant
Ce produit a fait de l’effet dès les premières heures. C’est incroyable !
N**L
Der Hund wird ruhiger ohne benebelt zu sein
Ein probates Mittel, um mit dem Hund etwas sorgloser über die Feiertage zu kommen. Man muss die Kauhappis täglich vorher eine Woche einschleichen, damit der Körper des Hundes sich daran gewöhnt. Und am Ende wieder langsam auschleichen. Der Hund ist von seinem Wesen nicht anders aber regt sich nicht so schnell auf und lässt sich schneller beruhigen. Und er wird auch nicht so dröge und benebelt wie mit anderen Mittelchen. Der Tip kam von zwei voneinander unabhängigen Tierarztpraxen. Wir haben die Kapsel immer aufgemacht und das Pulver in ein Stück Wurst versteckt. Die Kapseln hat er immer im Maul aussortiert und ausgespuckt. Wir werden das Mittel auch für längere Reisen verwenden. Es hat sich bewährt. Vielen Dank
C**I
Der absolute Wahnsinn, als Kur absolut empfehlenswert.Stress abbauend
Ich habe zyklene bei unserem stubentiger versucht, auf den Rat meiner Tierärztin .... Die Katze ist 13jahre alt und von klein auf sehr ängstlich, sie ist wenig schmusebedürftig und beim streicheln zuckte das Fell immer, wenn sie mal auf dem Boden lag und man ging weit entfernt vorbei schreckte sie jedesmal auf und rannte weg. Wirklich unentspannt. Da sie eh zum Tierarzt musste, fing ich drei Tage vorher an....allerdings hat sie nur eine täglich und nicht wie empfohlen für die drei Tage zweimal pro Tag bekommen. Schon am zweiten Tag hatte ich das Gefühl das Sie das Pulver über ihrem Fressen liebt, jede Futterzugabe vorher wurde gemieden...hier wurde sogar der Napf ausgeschleckt. Sie hat die Pillen insgesamt 40 Tage bekommen und jetzt seit Zwei Wochen nichts mehr. Sie ist anschmiegsamer geworden und legt sich sogar an mich dran, lässt sich kraulen und genießt es sichtbar und hörbar :) Absolut empfehlenswert, mein Mann war sehr skeptisch und wollte erst nicht das ich die Tabletten/Pulver gebe, jetzt ist er auch überzeugt und froh, denn auch er bekommt viele Schmuseeinheiten.
J**”
Decepcionada
Me parece surrealista que me llegue el producto como me ha llegado, totalmente decepcionante y cero confianza para administrárselo a mi perro.
Trustpilot
2 weeks ago
2 weeks ago